By Sriparna Roy and Leroy Leo

(Reuters) -CVS Health on Friday replaced CEO Karen Lynch with David Joyner, a CVS veteran who retired before returning to the company last year, after investors including activist Glenview Capital pressured the company to improve its stagnant share price.

It also withdrew its 2024 forecast and gave an outlook for third-quarter earnings far below analyst estimates.

CVS shares were down 7% on Friday. They are down by nearly half from their 2022 highs, in part due to quarter after quarter of repeated profit forecast cuts related to rising costs in its large healthcare insurance business and competition for its vast network of retail pharmacies.

Its third business - pharmacy benefit management - has been profitable but a focal point for U.S. government efforts to bring down U.S. drug prices. The Federal Trade Commission sued it and its rivals last month.

"The board believes this is the right time to make a change, and we are confident that David is the right person to lead our company," CVS Chairman Roger Farah said in a statement.

CVS on Friday said it expected adjusted profit of $1.05 to $1.10 per share for the quarter ended Sept. 30 compared to analysts' estimates of $1.70, according to data compiled by LSEG.

CVS was already growing rapidly beyond its retail pharmacy footprint when it bought health insurer Aetna in 2017, a move it said was needed to try to rein in healthcare costs and as it faced new healthcare competition from Amazon.com and others. In 2021, former Aetna executive Karen Lynch took over as CEO and the company's shares soared as it benefited from its role in the COVID-19 pandemic recovery.

Wall Street analysts have said that the company failed to find the benefits that could come from integration of different acquired businesses.

"This move was brewing for some time, as CVS has struggled under Lynch's leadership following the failed Aetna merger," said Oppenheimer analyst Michael Wiederhorn.

Glenview went public earlier this month with its concerns and sources said a strategic review that could include the split of the company's core businesses was on the table.

In a statement to employees, Joyner, who is on the board of directors, said that in order to succeed the company would need to operate as "one CVS Health."

Two sources familiar with the situation said CVS planned to remain as one company under Joyner.

Glenview said on Friday said that CVS needed to make changes to both leadership and the board.

"We believe the Company's culture, governance and leadership should be strengthened by those with both appropriate industry experience as well as fresh perspectives and that the Company would be best served through prompt Board evolution," it said in a statement.